Pharmaceutical Formulation Technology
Comprehensive Formulation Development
Stable Biologics employs Design of Experiment (DOE) formulation method, coupled with High-Throughput Screening (HTS) Technology to develop formulations from simple to complex formulation, starting with selection of buffers, individual excipients, to formulations consisting of a buffer and several excipients.
Formulation Support from Start to Finish
Stable Biologics has the capabilities to support biologics development from protein expression phase to clinical trials phase. Please see our Services for more details or simply contact us! We will be happy to assist your biologics development at any stages.
High-Throughput Formulation Screening
Stable Biologics laboratory designed an automated capillary self-interaction chromatography system such that it requires a very small amount of protein, as low as 1 ug, to perform a screening test. As a result, we can screen as many as 40 excipients in 2-4 week and only requires 20-30 mg of total protein.
Self-Interaction Chromatography Platform
Our formulation technology is based on the determination of the second virial coefficient, B22 value, a thermodynamic property of protein-protein interaction in a dilute solution via self-interaction chromatography method. B22 value can be measured via several ways, such as Dynamic Light Scattering, diffusion constant, kD, and self-interaction chromatography.
