Formulation Technology
Self-Interaction Chromatography Platform
Our technology is based on the determination of the second virial coefficient, B22 value, a thermodynamic property of protein-protein interaction in a dilute solution via self-interaction chromatography method. B22 value can be measured via several ways, such as Dynamic Light Scattering, diffusion constant, kD, and self-interaction chromatography.
High-Throughput Formulation Screening
Our laboratory designed an automated capillary self-interaction chromatography system such that it requires a very small amount of protein, as low as 1 ug, to perform a screening test.
As a result, we can screen as many as 40 excipients in 2-4 week and only requires 20-30 mg of total protein.
Comprehensive Formulation Development
Our DOE formulation method develops formulations from simple to complex formulation, starting with selection of buffers, individual excipients, to formulations consisting of a buffer and several excipients.
Formulation Support from Start to Finish
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